Page 47 - Community pharmcy practice E-book 2025
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01/11/2025, 22:08 Medication Errors & Constipation Management
Drug Interactions
Key Questions Definition
What are drug interactions? Drug interactions occur when the effects of
How Do Drug Interactions Occur? one drug are altered by the co-
What other factors cause interactions? administration of another drug, herbal
How do I check for drug interactions? medicine, food, drink or other
What should I do if I find a drug environmental chemical agents.
interaction? The net effect of the combination may
manifest as:
Additive or enhanced effect
Antagonism of the effect
Other alteration in the effect
What's Important?
Drugs with narrow therapeutic index: Theophyllin, digoxin
Drugs with steep-dose response curve: Anticoagulants
Pharmacokinetic interactions (INDUCER OR INHIBITOR)
Drugs with similar pharmacological effects
Extremes of age
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