Page 223 - Phytochemistry 2 (06-PG 605)

ii-Artemether:

lipid-soluble: for oral, rectal or i.m. use.
It has the longest half-life and also has the most toxicity
(related to high dosages) .
Its big advantage is that it can cross the blood-brainbarrier
It is the first-line drug for the treatment of cerebral malaria
iii-Dihydroartemisinin
iv-Artelinic acid

v-Artemoti

II- Diterpenes
Columbin

Source: obtained from sliced roots of calumba (Jateorhiza
Palmate), family Menispermaceae.
Uses:
Calumba is used as a bitter tonic. It contains no tannin, soit may
be prescribed with iron salts.