Page 221 - Phytochemistry 2 (06-PG 605)
P. 221

pancreatic and acute leukemia are characterized by more
 rapid cell division and thus higher iron concentrations
may respond better.

 Combination of artemisinin or its derivatives with transferrin (main
 protein in the blood that bind to iron and transports it through out
 the body), is useful in treating leukemia

 4-Artesunate also caused a defect in cytokinesis, i.e.cells
 had duplicated the DNA but could not divide properly
 (tetraploid cell, result in cell death).
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