Page 35 - Phytochemistry 2 (06-PG 605)

Pelletierine is an oily colourless volatile liquid

USES
Pelletierine tannate is official in the E.P.
It is mainly used as anthelmintic drug against pork tape worms and Ascaris
The tannate form of pelletierine is used because it is less soluble in GIT, so it is
less able to be absorbed (local action).
Conium alkaloids

Source:
isolated from hemlock fruits ( Conium maculatum).
The juice from hemlock plant was a primary constituent used by ancient Greeks in
executing criminals.
An extract of hemlock was used to cause the death of Socrates around 400 BC
The major alkaloid of hemlock is coniine. It is a toxic, liquid volatile alkaloid with
characteristic mice-like odor
Uses
Coniine has been used as a local analgesic , mostly in external preparations, due
to its high toxicity. It is used as an ointment for treatment of hemorrhoids and anal
fissures.

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