Page 136 - Biochemistry2 (08PB403)
P. 136
• RBC- most vulnerable as HMP is the only means for
NADPH production. (other tissues NADP-dependent
malate dehydrogenase also].
• Precipitating factors:
– Oxidant drugs [A-antibiotics (sulfamethoxazole),
A-antimalarial (primaquin), A-antipyritics
(acetanilide).
Ingesting
– Fava beans [favism]. in
– Severe infection-free radical generation
macrophages diffuse to RBC-hemolysis.
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