Page 136 - Biochemistry2 (08PB403)
P. 136

• RBC- most vulnerable as HMP is the only means for
   NADPH production. (other tissues NADP-dependent
   malate dehydrogenase also].

• Precipitating factors:

– Oxidant drugs [A-antibiotics (sulfamethoxazole),

A-antimalarial            (primaquin),  A-antipyritics

(acetanilide).

Ingesting

– Fava beans [favism].                      in

– Severe infection-free radical generation
  macrophages diffuse to RBC-hemolysis.

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