Page 134 - Biochemistry2 (08PB403)
P. 134

Mechanism

Normally, RBCs HMP shunt provides NADPH + H+ for
reduction of oxidized glutathione
(G-SS-G) to reduced glutathione (2 GSH) catalyzed by
glutathione reductase.

                                  Glutathione
G-SS-G + NADPH + H+ -------------- 2 G-SH + NADP+

                                   reductase

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