Page 134 - Biochemistry2 (08PB403)

Mechanism

Normally, RBCs HMP shunt provides NADPH + H+ for
reduction of oxidized glutathione
(G-SS-G) to reduced glutathione (2 GSH) catalyzed by
glutathione reductase.

Glutathione
G-SS-G + NADPH + H+ -------------- 2 G-SH + NADP+

reductase

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