Page 476 - Applied Pharmacognosy
P. 476

• Example: Rhubarb
• The % of total ash varies from 8 to 40 % in different samples

   of genuine Rhubarb .

• Therefore, a total ash figure is of no value for purposes of
   evaluation because it varies within wide limit .

• In case of drugs containing large and variable amounts of Ca
   oxalates ; the total ash is treated with dil. HCl and the % of
   acid insoluble ash is determined.

• The acid insoluble ash consists mainly of silica.

• A high acid insoluble ash in drugs such as Digitalis,
   Hyoscyamus, Liquorice, …..etc.
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