Page 240 - Applied Pharmacognosy
P. 240
How to solve ( overcome )
*Silanization
Reagents : (CH3)3SiCl, (CH3)2SiCl2 , (CH3)3SiN=NSi(CH3)3
OH OH → Si(CH3)3
Si O Si O O Si(CH3)3
Si O Si
active surface
(silanol) inactive surface
(trimethyl siloxy)
*H+ washing
239
