Page 240 - Pharmaceutics IV (02-06-01305)
P. 240

30/03/2024

    Formulation Development

                                   Dosage form
                    Factors affecting drug absorption

                        Formulation considerations

                                             Physiological

                                             Pharmaceutical

                       Dr ALyaa Ramadan, AU                  55

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    Factors affecting                              Drug concentration
     drug absorption                         Vehicle of drug delivery

                                               Mucosal contact time

                       Degree of drug’s ionization

                       pH of the absorption site

                       Size of the drug molecule

                                             Relative lipid solubility

                       Dr ALyaa Ramadan, AU                  56

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