Page 88 - Pharmaceutics IV (02-06-01305)
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Parenterals: Quality control testing
Foreign and particulate matter/ clarity testing
Visible particulates
• Although manual visual inspection is the most common means of
inspection, electronic particle detection equipment are replacing
manual inspection and using a light source or camera.
169
Parenterals: Quality control testing
Foreign and particulate matter/ clarity testing
Sub-visible particulates (particle count)
• For the determination of sub-visible (10 & 25 μm) particulate matter,
two procedures can be adopted: light obscuration particle count test)
and microscopic particle count test).
• Both are destructive tests (samples of the batch test).
170 85
Salma E. EL-Habashy
