Page 139 - Biochemistry PharmD General
P. 139
• RBC- most vulnerable as HMP is the only means for
NADPH production. (other tissues NADP-dependent
malate dehydrogenase also].
• Precipitating factors:
– Oxidant drugs [A-antibiotics (sulfamethoxazole),
A-antimalarial (primaquin), A-antipyritics
(acetanilide).
Ingesting
– Fava beans [favism]. in
– Severe infection-free radical generation 138
macrophages diffuse to RBC-hemolysis.
