Page 340 - Biochemistry PharmD General
P. 340

Ketone Bodies in Type 2 Diabetes

-FFA and KB are usually elevated (circulating KB may

increase 3 folds in non obese diabetics even if FFA
are normal).

-N.B. Why KB level is increased in type 2 diabetes
inspite of increased insulin (which should counteract
ketogenesis ) ?

Because of an also increased Glucagon, (with finally a
lower Insulin / Glucagon ratio)

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