Page 96 - Biochemistry PharmD General
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Functions of Gluconeogenesis
• Supply of body with needed glucose
– Glucose is the only source of energy for nervous
system, RBCs and skeletal muscles during exercise.
– Glucose is the precursor of milk sugar (lactose) in
mammary gland.
– Gluconeogenesis is essential during low carbohydrate
diet or when liver glycogen is depleted (after 12-18
hours of fasting).
• It clears the blood from waste products of other
tissues (e.g. lactate produced from muscles and RBCs)
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