Page 32 - controlled drug delievery
P. 32
Cont. Multiple unit systems
Pellitilization:
2. Extrusion-spheronization
Advanced wet granulation process aiming to produce perfect
spheroids for more uniform coating.
typical formulation of the wet mass for extrusion-spheronization is:
Parts by weight
Active drug 1-20
Lactose 60
Microcrystalline cellulose 40
Binder 2-10
Water 40
