Page 52 - General Biochemistry
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Effect of temperature
• Higher temperature increases the number of effective collisions and therefore
increases the rate of a reaction.
• Above a certain temperature, the rate begins to decline because the enzyme
protein begins to denature
Figure 15 effect of temperature
Effect of pH
• Each enzyme has an optimal pH at which it is most efficient
• A change in pH can alter the ionization of the R groups of the amino acids.
• When the charges on the amino acids change, hydrogen bonding within the
protein molecule change and the molecule changes shape.
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