Page 78 - phytochemistry I - PharmD Clinical
P. 78

2- Monocyclic monoterpene alcohols:

Menthol

Source:  Japanese peppermint                               (Mentha arvensis).

                                                                               OH

Preparation of menthol from peppermint oil:

The solid portion separated from the volatile oil by cooling is called
"stearoptene", and the liquid portion is called "eleoptene".

    Synthesis of menthol:

         OH HydHr2ogenatiOoH n

Thymol       dl-menthol
         Racemic mixture

Menthol and thymol separation:

                                                       ۷٦
   73   74   75   76   77   78   79   80   81   82   83