Page 239 - BIOCHEMISTRY II
P. 239
Stage 3: Condensation of six
activated isoprene units to
form squalene
Isopentenyl phosphate and
dimethylallyl phosphate undergo
a “head-to- tail” condensation
in which two phosphate group is
displaced and a 10- carbon
chain (geranyl phosphate) is
formed.
Another “head-to-tail”
condensation→ 15-carbon
farnesyl pyrophosphate