Page 24 - 01 CARBOHYDRATES for TCM

Antidepressant Evaluation of Polysaccharides from a Chinese Herbal

Medicine Banxia-houpu Decoction

 半夏 ban xia (pinellia tuber, 120 g) ; Pinellia ternata (Thunb.)
 木兰属 mu lan shu (magnolia bark, 90 g) ; Magnolia officinalis Rehd. Et Wilson

 茯苓 Fú Líng (hoelen, 120 g); Poria cocos Wolf.

 紫苏 zi su (perilla herb, 60 g); Perilla frutescens (L.) Britton
 姜 jiang (ginger rhizome, 90 g); Zingiber officinale Roscoe.
Banxia-houpu Decoction designed for the treatment of liver qi

stagnation and phlegm accumulation

 Banxia-houpu decoction were active in animal models of

depression with comparable effects to known antidepressants.

 The oral administration of the polysaccharides at a low dose

for 4 weeks resulted in a significant increase in the monoamine

neurotransmitter 5-hydroxytryptamine (5-HT) and dopamine

(DA) levels in whole mouse brain