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General Microbiology & Immunology (PM 401)         Second level                Semester 4                    2024/2025


                  1 - Endocytosis


                        A. Phagocytosis (cell eating)

                                                                            .
                             Ingestion of solid particles by endocytosis

                  The cytoplasmic membrane folds inward and pinches off placing the

                  particle in a phagocytic vacuole. The phagocytic vacuole then fuses

                  with  lysosomes   forming  a  phagolysosome  and  the  material  is

                  degraded


                      B. Pinocytosis (cell drinking)


                             Ingestion of dissolved materials by endocytosis


                  The cytoplasmic membrane folds inward and pinches off placing small

                  droplets  of  fluid  in  a  pinocytic  vesicle.  The  liquid  contents  of  the

                  vesicle is then slowly transferred to the cytosol

                     C. Receptor- Mediated Endocytosis


                           Movement of very specific molecules into the cell with
                           the use of vesicles coated with protein.

                   •  When specific molecules bind to the receptors in coated pits, then

                      this stimulates the molecules to be engulfed into a coated vesicle.


                  2- Exocytosis

                    During exocytosis ,a cell releases waste products or specific secretion products

                    by the fusion of a vesicle with the cytoplasmic membrane










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