Page 37 - PC 101 Interactive practical book
P. 37

MANSOURA NATIONAL UNIVERSIY
         PHARM D- CLINICAL PHARMACY                        LEVEL I                        PHARM. ANAL. CHEM. I (PC 101)



                      How to predict the shape of the titration curve?


                                                                                End of the curve



                               pH of                            If higher        predicted from
                             the titrated                        concn.         pH of the titrant

                              solution



                                                                 If lower
                                                                 concn.



                                                                    Middle of the curve
                                                                       predicted from
                                                                     pH of the products
                                                                 (= pH at equivalence point)


              Start of the curve
                predicted from                                                  mls added
               pH of the sample                                                 of the titrant




           The pH-range of the indicator:

             It is the pH-range ( pH-interval ) within which the indicator changes its


             color.


             Ex.: - The pH-range of M.O. ≈ (3 – 4.5) approximately.


                   - The pH-range of ph.ph. ≈ (8.5 – 10) approximately.





















          37 | P a g e
   32   33   34   35   36   37   38   39   40   41   42