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MANSOURA NATIONAL UNIVERSIY
PHARM D- CLINICAL PHARMACY LEVEL I PHARM. ANAL. CHEM. I (PC 101)
Volhard method Cl - , Br - , I - & SCN - . Back (Residual) titration. 1 st standard (25 ml): AgNO3. 2 nd standard (titrant): NH4SCN or KSCN. Acidic medium (HNO3). Ferric alum = Ferric ammonium Sulfate { FeNH4(SO4)2.12H2O }. OR 2) Ferric nitrate { Fe(NO3)3 }. Faint orange or faint red color.
1)
Mohr's method Cl - , Br - (Not for I - or SCN - ). Direct titration. Standard AgNO3. Neutral or slightly alkaline. (pH ≈ 6.5 -9). 1 ml of 5% Pot. Chromate (K2CrO4) solution. First permanent darkening of the yellow chromate color [due to the formation of Ag2CrO4 (brick red ppt) at the end point leading to darkening of the solution].
Sample E.P color change
Type of titration Standard Solutions pH Indicator
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