Page 48 - Imprint-magazine june-Issue

Dissolution is a test used by the Pharmaceutical
industry to characterize the dissolution
properties of the active drug, the active drug’s
release, and the dissolution from a dosage
formulation.

Xtend™ Dissolution Testing

from Sotax

Whether you perform routine testing in QC
or need to execute DOE studies in R&D –
SOTAX systems allow flexible automation
of your dissolution tests as needed
XtendTM Dissolution Testing
Different dissolution testing methods are described in
USP, Ph.Eur., and other internationally harmonized Phar- Highlights
macopeia as well as in FDA guidelines. Whereas stan-
dard tablets are typically tested according to the paddle 100% Visibility.
method (USP 2), swelling or floating dosage forms such
as capsules are tested using the basket method (USP 1). Compliance by Design.
Paddle-over-disk (USP 5) and rotating cylinder (USP 6) SOTAX dissolution testers are
methods are used for transdermal dosage forms. compliant by design. Proven to
have the lowest wobble rating in
Xtend™ allows flexible automation of your dissolution pro- the industry, no adjustments are
cesses. Standardized Xtend™ modules can be combined to required with fixed shaft height.
differently automated dissolution systems - making meth- Highly accurate vessel centering
od transfer and scale-up easier than ever. From manual with quick-lock system ensures
baths to semi-automated systems to fully automated dis- fast change-over and easy handling. Simply close your bath and
solution tester with multiple networked systems, Xtend™ you are ready to go. Ease of regulatory compliance without
is one platform for all your dissolution needs. time-consuming adjustments.

Automated - manual to Simply see what’s
happening in each
100% unattended operation dissolution vessel. The
unique bath design allows
with self-cleaning obstruction-free
observation from the
outside and from the
inside with Center-
• Innovative modular design allows ViewTM video
flexible system configurations according to your monitoring. At the same
requirements time, the round shape
• Automate as needed - from manual to 100% ensures optimum water circulation for temperature
unattended operation with self-cleaning homogeneity and easy cleaning without any corners.
• Simplified method transfer and scale-up with
identical components for all automation levels
• Flexible sampling & filtration - mimic existing
environments
• All your data in one place with built-in data
integrity and fail-safe networking of multiple
testers
• Compliance by design - readily accepted by
regulatory authorities world-wide
• Automate as needed - from manual to 100%
unattended operation with self-cleaning

48 JUNE-2021