Page 31 - Practical Handout bio 2 mnu 2025_Neat
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Level two – Semester 4 - PharmD      Biochemistry-II PB-403 (Practical course)     2024/2025


                                                        1.  Volume

                        Normal urine output                               1-2 L/day

                               Polyuria                             Volume > 2 L / day

                               Oligouria                            Volume < 1 L / day


                                Anuria                                No urine output
                                         Factors affecting urinary output:


                                                            ❖ A high protein diet increases

                       a)  Diet                                urea and so increases urine output.

                                                            ❖ Xanthine beverages: polyuria

                       b) High fluid intake                               polyuria


                                                               Winter                 Summer

                       c)  Temperature
                                                           ↓ perspiration          ↑ perspiration

                                                         causing polyuria.        causing oliguria.

                       d) Pathological cases                Diabetes mellitus causes polyuria

                       e)  Drugs                                     Diuretics: polyuria



                                                         2.  Odor

                                                    faint aromatic odor due to the presence of
                     Normal           Fresh
                                                    volatile organic acids.
                      urine
                                  On standing       urea      bacteria       ammonia odor

                                   Ripe apple-
                                                    presence of acetone in diabetes mellitus.
                      Odor          like odor

                    changes                         due  to  the  presence  of  pus  cells  and
                                    Very bad
                                                    epithelial  cells  in  bilharziasis  or  renal
                                       odor
                                                    inflammation.










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