Page 59 - Practical DF2 Corrected (2)
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Pharm D Clinical Pharmacy program 2024-2025 Level 2, Semester 2 Pharmaceutical Dosage Forms II (PT 405)
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Method of preparation:
1. Finely powder sulfur and resorcinol and levigate with one ml of glycerin.
2. Melt stearic acid on a water bath, then raise the temperature to 75–80 °C.
3. Dissolve potassium hydroxide in distilled water and heat to 75–80 °C.
4. Add (2) to (1) with vigorous trituration.
5. On a watch glass, levigate the mixture of sulfur and resorcinol with 1 ml of
glycerin.
6. Add the levigated drug to the formed cream while on water bath, and
triturate.
7. Remove from heat, and continue trituration until a homogenous cream is
obtained.
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