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Pharm D Clinical Pharmacy program 2024-2025  Level 2, Semester 2  Pharmaceutical Dosage Forms II (PT 405)

                      Acne Vulgaris Cream

• Sebaceous glands are sac-like structures which usually open to the skin surface
   by way of the canals of the hair follicles.

• The condition acne vulagaris involve enlargement of the sebaceous glands and
   bacterial infection of the follicular opening.

• The blackhead or comedone, and abnormal mass of keratin and sebum within
   the follicular opening are a mild manifestation of this disorder, but this may
   proceed to varying degrees of inflammation.

• Acne generally starts about puberty and usually cures itself during the twenties
   (mainly due to hormonal regulation).

The formula for preparation of acne vulgaris cream is the following:

Rx/

     Sulfur                  5g

     Resorcinol              2g

     Potassium hydroxide     0.74 g

     Stearic acid            15 g

     Glycerol                5g

     Distilled water      to 100 g

     Fiat cream. Mitte 15 g

Calculations:

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