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Carbon Dioxide Laser and Aphthous stomatitis

significant reduction in pain intensity. However, in terms Khiabanloo S, Safar F, et al. Relieving pain in oral lesions of
of healing time, satisfaction, and daily dysfunction, no pemphigus vulgaris using the non-ablative, non-thermal,
significant difference was observed in different groups. CO laser therapy (NTCLT): Preliminary results of a novel
23
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In the present study, about changing the size of RAS approach. J Lasers Med Sci. 2017;8(1):7-12. doi: 10.15171/
ulcers following the treatment in the three control groups jlms.2017.02.
on third, fifth and seventh days after the treatment in 8. Vincent SD, Lilly GE. Clinical, historic, and therapeutic
features of aphthous stomatitis. Literature review and
comparison with before the treatment, there was no open clinical trial employing steroids. Oral Surg Oral
significant difference. In a study by Prasad and Pai using Med Oral Pathol. 1992;74(1):79-86. doi: 10.1016/0030-
a continuous CO laser with the power of 0.7 W, lesion 4220(92)90219-g.
2
healing was studied on days 3 and 4 after the treatment 9. Ship JA. Recurrent aphthous stomatitis. An update.
and every two days for up to two weeks. The reduction Oral Surg Oral Med Oral Pathol Oral Radiol Endod.
of the erythematous halo around the aphtha and the 1996;81(2):141-147. doi: 10.1016/s1079-2104(96)80403-3.
complete ulcer removal meant to be aphtha healing. The 10. Davatchi F, Tehrani-Banihashemi A, Jamshidi AR, Chams-
results of this study showed the duration of ulcer healing Davatchi C, Gholami J, Moradi M, et al. The prevalence of
in the laser group was shorter than that of the placebo oral aphthosis in a normal population in Iran: A WHO-
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group. This difference in the present study can be due to ILAR COPCORD Study. Arch Iran Med. 2008;11(2):207-
different average power and hours of follow-up and also 209.
the difference in the indicator of ulcer healing. The results 11. Alidaee MR, Taheri A, Mansoori P, Ghodsi SZ. Silver
nitrate cautery in aphthous stomatitis: A randomized
of this clinical trial showed that the carbon dioxide laser, controlled trial. Br J Dermatol. 2005;153(3):521-525. doi:
whether with continuous radiation or pulsed radiation, 10.1111/j.1365-2133.2005.06490.x.
can be used to relieve the pain of minor aphthous lesions. 12. Belenguer-Guallar I, Jiménez-Soriano Y, Claramunt-
The high cost of laser therapy was one of the limitations Lozano A. Treatment of recurrent aphthous stomatitis. A
of our study, but no cost was incurred by the patients in literature review. J Clin Exp Dent. 2014;6(2):e168-74. doi:
this regard. 10.4317/jced.51401.
13. Arikan OK, Birol A, Tuncez F, Erkek E, Koc C. A
Ethical Considerations prospective randomized controlled trial to determine if
This randomized and interventional clinical trial study cryotherapy can reduce the pain of patients with minor
was done on patients referred to the clinics and offices form of recurrent aphthous stomatitis. Oral Surg Oral Med
in Urmia after obtaining permission from the Ethics Oral Pathol Oral Radiol Endod . 2006;101(1):E1-5. doi:
10.1016/j.tripleo.2005.07.035.
Committee of Urmia University of Medical Sciences with 14. Jijin M.J, Rakaraddi M, Pai J, Jaishankar HP, Krupashankar
IR.UMSU.Rec.1396.364 registration number, and written R, Kavitha AP, et al. Low-level laser therapy versus 5%
informed consent was obtained from all the patients. Amlexanox: A comparison of treatment effects in a cohort
of patients with minor aphthous ulcers. Oral Surg Oral
Conflict of Interests Med Oral Pathol Oral Radiol. 2016;121(3):269-273. doi:
The authors declare that they have no conflict of interest. 10.1016/j.oooo.2015.11.021.
15. Stanbury R, Graham E. Systemic corticosteroid therapy:
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