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Surgery  Case series


 Kinematic alignment technique in total knee   Heterotopic ossification after total hip

 arthroplasty  arthroplasty





 Dr. Santoshkumar   Minimizes the stress on ligaments by decreasing the   Dr. Raghuvansh Kumar   II revision surgery  [2]
 anatomical change of bone
 [1]
 Hakkalamani  Safe   and   accurate   approach   with   generic   Pandey  The patient reported with recurrent left hip pain 1.5
                                                                  years after first revision, with an elevated CRP level
 instrumentation  [1]                                             (range: 0.7-2.6mg/dL).
 Joint Replacement and Arthroscopy
 Preserves the original knee kinetics  [1]  and improves   HOD - Orthopedics &  Joint Replacement  A second revision surgery was then performed via a
 BGS Global Gleneagles Hospitals, Bengaluru  knee balance  [2]
       Venkateshwar hospital, New Delhi                           posterior approach.
 [2]
 Better  soft-tissue  tension    and  provides  a  more           The surgeon excised the scar tissue, removed existing
 Introduction  normal feeling knee than those treated with MA  [3]  Introduction  osteophytes  and  excessive  cement  around  the
                                                                  proximal site of the stem to allow the removal of the
 Total knee arthroplasty (TKA) is the definitive surgical   Clinical evidence  Heterotopic ossification (HO) is any bone formation   well-fixed femoral stem.
 option for advanced osteoarthritis of knee.  [1]
 Following  is  the  compilation  of  a  deluge  of  clinical   in  the  soft  tissues  that  develops  after  surgery  or   Antibiotic prophylaxis  [2]  Outcome  [2]
 There  is  a  high  dissatisfaction  rates  of  up  to  20%   evidence derived from studies involving KA-TKA:  without a well-defined precipitating event.   [1]
 reported in uncomplicated TKA [1] and this leads to a              Oral antibiotics were   At the latest follow-up, the
 search for accurate recreation of the constitutional (or   Study  Study design  Conclusion  Prevalence and etiology  patient did not report any
 pre-arthritic) alignment of the knee  [2]                          prescribed (minocycline +
 Hsu et al.   Prospective study to   All five knee phenotypes   The reported rates of HO after total hip arthroplasty   sulfamethoxazole-  left hip pain, and the CRP
 The kinematic alignment (KA) technique in TKA aims   (2020)  assess clinical   significantly improved   (THA) range widely from 2% to 90%,  [1]  trimethoprim) to the patient   level remained within the
 functional outcomes with a
 outcome in 122
 to  restore  the  native  alignment  of  the  knee  joint   patients (139 knees)  total survival rate of 99.3%   for 3 months after   normal range for >3years.
                                                                                            The patient’s hip function
 anatomy  based  on  the  five  most  common  knee   at 3-year follow-up.  [1]  Although  the  cause  of  HO  remains  unclear,   II revision surgery.  improved, and the PJI was
 phenotypes.   [1]  MacDessi et al.   Randomized   Restoring the constitutional   periprosthetic joint infection (PJI) after THA is often   controlled following two
 (2020)  superiority trial   alignment with KA in TKA   implicated.   [2]                   revision surgeries.
 comparing KA to   results in a statistically
 Surgical protocol  MA in a total of 125   significant improvement in   Radiation  and  NSAIDs  are  effective  aids  for
 patients (138 knees)  quantitative knee balance  [2]  prophylaxis of HO.
 Individualized  alignment  targets  are  set  for  each   KA group had less bone recuts   Conclusion
 patient according to each patient’s knee phenotype to   and tibiofemoral lift-offs  [2]
 compared to MA group.
 perform KA-TKA. (Figure 1)   [1]  Operative Intervention         The  management  of  HO  in  the  presence  of  PJI  is
 Howell et al.   Level III 10-year   KA-TKA did not adversely     difficult.  [2]
 (2018)  follow-up study   affect the implant survival,   Though an effective option, surgical excision should
 Type I (Neutral)  No adjustment  involving 217   yearly revision rate and level   be  considered  only  for  patients  with  functional   In such cases, a dual approach to the hip has to be
 [3]
 patients (222 knees)  of function                                practised to enhance clearance of the HO.  [2]
       deficits as a result of HO.   [3]
 Conclusion                                                       Antibiotics  should  be  administered  intravenously
 LDFA: 87  Timing  of  intervention  is  different  for  different
 Type II (Neutral)                                                following THA, with consideration of additional oral
 MPTA: 87
 Evidence  supports  the  restoration  of  knee  joint   etiologies.  For  HO  following  THA,  early  excision  is   antibiotics for patients with a PJI.  [2]
 alignment  with  individualized  target  according  to   recommended  as  it  allows  better  differentiation  of
 LDFA: 87-90
 Original   MPTA: 85-87  original knee phenotype establishing KA as a viable   the ectopic bone from normal callus and scar at the   References
 Type III (Varus)
 phenotype  Medial soft tissue relase  alternative to MA.  operated site. [3]
 Reduction osteotomy
                                                                  1.  Iorio,  Richard  MD;  Healy,  William  L.  MD  Heterotopic
 LDFA: 90-93  References                                          Ossification  After  Hip  and  Knee  Arthroplasty:  Risk  Factors,
 Type IV (Varus)  MPTA: 85-87  Case report of a complex HO        Prevention, and Treatment, Journal of the American Academy of
 Medial soft tissue relase
 Reduction osteotomy  1. Hsu et al. Total knee arthroplasty according to the original knee   I revision surgery  [2]  Orthopaedic Surgeons: November 2002 - Volume 10 - Issue 6 - p
 phenotypes with kinematic alignment surgical technique—early     409-416
 LDFA: 87  clinical  and  functional  outcomes.  BMC  Musculoskeletal   A 78-year-old male patient who underwent cemented   2.  Yutaka  Kinoshita,  Shunji  Nakano,  Shinji  Yoshioka,  Masaru
 Type V (Valgus)  MPTA: 90  Disorders (2020) 21:839               Nakamura, Tomohiro Goto, Daisuke Hamada, Koichi Sairyo, "A
 Lateral soft tissue relase  THA, 17 years earlier reported with severe HO.  Rare  Case  of  Extremely  Severe  Heterotopic  Ossification  after
 2.  MacDessi SJ, Griffiths-Jones W, Chen DB, et al. Restoring the
 Figure 1- Target angles of LDFA and MPTA according to original phenotype of knee  constitutional  alignment  with  a  restrictive  kinematic  protocol   Revision  THA  was  performed  using  a  direct  lateral   Primary  Total  Hip  Arthroplasty  due  to  Persistent  Mild
 Abbreviations: LDFA-lateral distal femur angle; MPTA- medial proximal tibial angle  approach.  Periprosthetic Joint Infection", Case Reports in Orthopedics, vol.
 improves  quantitative  soft-tissue  balance  in  total  knee    2021, Article ID 8849929, 7 pages, 2021.
 KA-TKA Advantages  arthroplasty:  a  randomized  controlled  trial.  Bone  Joint  J.   The surgeon excised the HO, removed the loosened   3.  Ranganathan  K,  Loder  S,  Agarwal  S,  et  al.  Heterotopic
 2020;102-B(1):117-124.
       acetabular  cup  and  fibrous  tissue,  and  placed  an     Ossification:  Basic-Science  Principles  and  Clinical  Correlates
 Restores the pre-arthritic knee joint by resecting bones   3.  Howell SM, Shelton TJ, Hull ML. Implant Survival and Function   allograft.  [published correction appears in J Bone Joint Surg Am. 2015 Sep
 parallel to the joint line of the femur and tibia   [1]  Ten Years After Kinematically Aligned Total Knee Arthroplasty. J   2;97(17):e59.
 Arthroplasty. 2018;33(12):3678-3684.   Femoral stem was not replaced due to hip ankyloses.
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