Page 15 - BIO REX PAPAYA English
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Anti-Tumour
In general, natural cancer prevention & treatment depends
mainly on immune cells, such as monocytes, macrophages and
natural killer (NK) cells. It has been reported that these cells
act on cancer prevention while their absence increases cancer
risk. Thus, the anti-tumor immune system is considered a
potential target for cancer therapy. To elucidate the
mechanisms of the anti-tumor effect of Fermented Papaya,
scientists concluded that Fermented papaya supplementation
can activate immune function in vitro. IL-1β, TNFα and IFNγ
released by immunocytes are involved in numerous
immunological and inflammatory reactions and hence inhibit
tumor progression (Li et al., 2014).
Another in vivo study done by Murakami et al (2016)
demonstrated the cancer fighting capabilities of fermented
papaya. Mice were injected with RL male 1 cells
subcutaneously or 3-methylcholantherene (MCA)
intravenously to induce cancer and orally or intraperitoneally
treated with fermented papaya solution. Administration of
fermented papaya suppressed tumor size and the incidence
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