Page 19 - BIO REX PAPAYA English
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Liver Diseases
A group of Italian, French and Japanese scientists coordinated
a series of studies on the alcoholic liver disease which proved
how fermented papaya reduces the alcoholic oxidative stress
on liver (reduction of plasma and erythrocyte level of
malonyldialdehyde as well as of plasma lipoperoxides). The
results indicated that in chronic liver diseases caused by
alcohol consumption, fermented papaya preparation
increased the content of glutathione in red blood cells, and
decreased their reactive oxygen species generation,
membrane lipid peroxidation, indicating amelioration of their
oxidative status.
On the other hand, Non-alcoholic steatohepatitis (NASH) can
progress to cirrhosis or hepatocellular carcinoma. Oxidative
stress is implicated in NASH progression. Murakami et al (2013)
investigated the effects of FPP on NASH progression using a
rat NASH model. Plasma biochemical parameters and lipid
peroxidation in the liver were elevated in NASH rats. Oral
administration of Fermented Papaya ameliorated these
changes in NASH rats. These results suggest that fermented
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