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Type-2 Diabetes
Patients suffering from diabetes-caused oxidative stress have
a greater risk of developing cardiovascular diseases,
neuropathy, congenital malformations and retinopathy.
Glycation products from excess glucose can chemically modify
DNA causing mutations and cause complex DNA
rearrangements. Oxidative stress is increased in diabetes
because of glucose oxidation and factors that include cellular
redox imbalances and reduction in antioxidant defenses
comprising decreased cellular antioxidant levels and a
reduction in the activity of enzymes that remove free radicals.
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