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Wound Healing on Type-2 Diabetic Patients
Oral supplementation with fermented papaya preparations
significantly corrected metabolic and oxidative stress markers
in patients with type 2 diabetes, according to few clinical trials
by Dickerson & Collard, 2010-2015. Fermented Papaya
contributed to the acceleration of wound healing in animals
and humans. The wound healing effect depended mainly on
the removal of necrotising tissue, reduction of bacterial
resistance to granulocytes attack, and speeding-up the
epithelization [Mikhal'chik, 2004]. This clinical research has
shown that local application of Bio Rex Papaya to the wounded
skin resulted in a fast granular tissue formation and
accelerated epithelization.
Nayak et al (2006) examined effects of fermented papaya
against diabetic wounds on rat model. Extract-treated animals
exhibited 77% reduction in the wound area when compared
to controls which was 59% (see diagram below). The extract
treated wounds were found to epithelize faster as compared
to controls. The extract also exhibited antimicrobial activity
against the five organisms tested. Hence, they concluded that
fermented Carica papaya promotes significant wound healing
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