Page 52 - D:\Video IPSyoFS22\

Isolated compounds with anti-convulsant activity: a review

1 Panjugula Manisha, Avulapati Tejaswini, Theepalapudi Nageswari, Konda Swathi*
1
1
1

1 Sri Padamavathi mahila Vishwavidyalaya, Tirupati,517101, India.

* Corresponding author: kswathi84@yahoo.co.in

Abstract:

Epilepsy refers to a set of illness marked by repeated spontaneous seizures that appear to be the
consequences of complicated processes involving diverse neurotransmitters, including much of the
glutaminergic, cholinergic and gabaergic systems. Over 450 million people worldwide, according to the
WHO, have are some points in their dealt with mental, neurological or behavioral difficulties. An estimated
50 million people worldwide suffer from epilepsy, with countries with lower middle incomes accounting
for higher than 85% of instances.221 taxa from 53 plant families were included as epileptic therapies in
th
nine of the most significant European herbal remedies of the16 and 17 centuries. The drug influence brain
th
neurotransmitters or alter the permeability of all membranes to ions, depending on the condition. Potential
therapeutic medication candidates can be found in medicinal plants. New medical plants are being
introduced around the world in order to generate effective, cost-efficient, and safe medications. Natural-
source drugs have fewer adverse effects and better working potential. Herbal medicines can have less
adverse effects than medicinal drugs. This article gives information about the isolated compounds for
anticonvulsant activity and useful for future investigators.

Keywords: WHO, Natural products, Anti-convulsant activity, Isolated compounds, Epilepsy.