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QUICK REFERENCE                                         MANAGEMENT OF BIPOLAR DISORDER (2ND EDITION)



               Relative infant dose (RID): 12.2%    Possible to use cautiously     Possible to use in lactation     RID: 5 - 31%    Possible to use in lactation     Possible & compatible     RID: 0.7 - 8.3%    Not recommended during lactation    Not recommend
           LACTATION









           PREGNANCY   Human data suggest risk   Contraindicated    Compatible   Not recommended for BD   Human data suggest low risk   No human data - animal data   suggest moderate risk  No human data - animal data   suggest moderate risk  Limited human data - anima
         ADVERSE EFFECTS & USE OF MEDICATIONS IN PREGNANCY & LACTATION







            Mood stabilisers   Antipsychotics            Selective Serotonin Reuptake Inhibitor  RID  <10%  is  considered  compatible  with  breastfeeding.  However,  worth  noting  that  some  sources  recommend  that  for  psychotropic  agents,  breastfeeding  is


           COMMON/SIGNIFICANT ADVERSE EFFECTS  Polyuria, polydipsia, weight gain, hyperparathyroidism, hypothyroidism, fatigue, acne,  dysgeusia, diabetes insipidus, fine tremor, gastrointestinal (GI) upset  Raised liver enzymes, GI upset, fatigue, drowsiness, weight



















           MEDICATION   Lithium    Valproate   Lamotrigine   Carbamazepine   Aripiprazole   Asenapine   Cariprazine    weight gain   Haloperidol   Lumateperone   Lurasidone   somnolence   Olanzapine   Paliperidone   somnolence, tremor   Quetiapine   somnolence   Rispe




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