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Clinical pharmacy PharmD program Third level Phytochemistry-1 (PG-504)

Desoxysugar or deoxysugars, in which one or more of the hydroxyl groups

of the corresponding aldose or ketose has been replaced by hydrogen, occur

widely throughout nature. They are formed from the parent sugar by the removal

of an oxygen atom from either a secondary or a primary alcohol group, to produce

a (-CH 2-) or a (CH 3) group, respectively. They are more reactive than the parent

sugar.

They are classified into:

a) 2-Desoxy-hexoses. b) 6-Desoxy-hexoses. c) 2, 6-Didesoxy-hexoses.

a) 2-Desoxy-sugars = 2-desoxy-pentoses

They are monosaccharides in which -OH group at C-2 has been replaced by H

Importance and Example: 2-deoxy ribose: the sugar found in DNA

a) 6-Desoxy - sugars

The removal of an oxygen atom from the terminal -CH 2OH group of a

hexose, gives rise to 6-desoxy-sugar, which are regarded and named as methyl

pentose. 6-desoxyhexose, such as L-fucose, L-rhamnose, and D-digitalose are

found in many polysaccharides, and plant glycosides.

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