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PF DTFC
No. of documented No. of patients
Previous treatment %
patients improved
Bimatoprost 44 43 97.7
Brimonidine 49 46 93.9
Metipranolol 39 35 89.7
Latanoprost 98 87 88.8
Latanoprost/timolol 44 39 88.6
Travoprost 73 64 87.7
Brimonidine/timolol 52 44 84.6
Dorzolamide/timolol 263 221 84.0
Brinzolamide 59 49 83.1
Dorzolamide 80 65 81.3
Timolol 282 227 80.5
Travoprost/timolol 29 23 79.3
Total 1438 1216 84.6
Table 6: Improvement of local tolerability under monotherapy with PF DTFC
CONCLUSIONS: In Switching to preservative-free combination of dorzolamide/timolol improves local tole-
rability and the drug was well tolerated in the vast majority of patients.
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