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EFFICACYOLERABILITY
EFFICACY /T
KEY MESSAGES
X Compared to preserved eye drops, PF preparations were significantly less associated
with ocular symptoms.
X Local tolerability improved in 84.6% of patients compared to their previous glaucoma
treatment.
X In daily practice, switching to DTFC improves local tolerability.
STRENGTHS
X A 3-month prospective study (2298 patients) evaluating tolerability of PF DTFC.
X The results of this study underline the good tolerability, the safety profile with low inci-
dence of adverse events, and the pronounced IOP-lowering.
X This study adds further evidence concerning the benefit of PF eye drops in glaucoma
treatment.
WEAKNESSES
X Open study – non interventional
MARKETING CLAIM
X Switching from preserved treatment to unpreserved Dorzolamide-Timolol combination
improves local tolerability.
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