Page 39 - DUOKOPT BIBLIOBOOK
P. 39

EAS  EFFICACYY HANDLING







                   X    Eye dsiconfort (5 events) and decreased lacrimation (3 events), foreign body sensation,
                     irritation, pruritus, hypersensitivity, hyperaemia, dry eye, oedema and erythema were the
                     most often reported adverse events.


                 CONCLUSIONS: The tested multi-dose delivery system is highly accepted in the studied

                   X    population and is a suitable choice for a fixed-combination glaucoma therapy. Further
                     studies may be necessary to assess the easiness of use of this easy-to-grip delivery
                     system in patients with greater disability to instill or having severe problems in instilling
                     their eye drops themselves.



                    KEY MESSAGES



                   X   Real-life data for an international study designed for both ophthalmologist and patients
                   X    78.3% patients and 97% of the ophthalmologists are satisfied with the multidose delivery
                     system: Easygrip
                                      ®
                              ®
                   X    Easygrip  MD patented bottle is highly accepted in the studied population with different
                     levels of visual acuity or levels of dexterity
                   X    The study reports satisfaction results for opening, handling, squeezing and obtaining a
                     drop as well as instilling eye drops using Easygrip  MMDS.
                                                                      ®
                                                          ®
                   X    Good  compliance  with  the  EasyGrip   system  with  80%  of  patient  that  almost  never
                     forget their eye drops.
                                                                                            ®
                   X    The results confirm the interest of switching to the PF MD device EasyGrip  whilst keeping
                     the efficacy.
                   X    Education of patients on the good instillation technique is key to keep a long-term
                     adherence and ultimately the treatment efficacy.

                    STRENGTHS


                                                                             ®
                   X    First real-world data on patient satisfaction with Duokopt , and first study where dexterity
                     problems were assessed with Quick Dash questionnaire in glaucoma population.
                   X    The results of ISY study confirm the interest of switching from a preserved MD glaucoma
                                                                          ®
                     treatment to a Preservative-free MD device EasyGrip  whilst keeping the efficacy. This
                     new MD patented bottle is well accepted even in an elderly population with differing
                     levels of visual acuity.


                    LIMITATIONS


                   X   No  comparison to another multidose.
                   X   Design with only one visit
                                                   ®
                   X   Different durations of Duokopt  use before evaluation

                    MARKETING CLAIM


                                                                                     ®
                   X    The New Preservative-Free Multidose delivery system Eeasygrip  is considerer easy to
                     use by glaucoma patients.


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