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                    KEY MESSAGES


                 ‐    1 month study (15 patients) evaluating DTFC on IOP, visual function and ocular hemodynamics.
                 ‐    Intraocular pressure was significantly reduced by dorzolamide-timolol combination as compared with
                 timolol alone.






                    STRENGTHS


                   X    The dorzolamide-timolol combination accelerated superior temporal arterial arterio-
                     venous passage of fluorescein dye as compared with timolol treatment alone, from 2.13
                     to 1.76 seconds.

                   X    DTFC reduces the amount of time required for blood to pass through the superior retinal
                     vasculature.




                    WEAKNESSES


                   X   Low number of patients (15).



                    MARKETING CLAIM


                   X    Dorzolamide-Timolol combination  reduces  IOP  and  increases ocular  blood  flow
                     compared to Timolol.








































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