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KEY MESSAGES
‐ 1 month study (15 patients) evaluating DTFC on IOP, visual function and ocular hemodynamics.
‐ Intraocular pressure was significantly reduced by dorzolamide-timolol combination as compared with
timolol alone.
STRENGTHS
X The dorzolamide-timolol combination accelerated superior temporal arterial arterio-
venous passage of fluorescein dye as compared with timolol treatment alone, from 2.13
to 1.76 seconds.
X DTFC reduces the amount of time required for blood to pass through the superior retinal
vasculature.
WEAKNESSES
X Low number of patients (15).
MARKETING CLAIM
X Dorzolamide-Timolol combination reduces IOP and increases ocular blood flow
compared to Timolol.
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