Page 89 - Critical Maternity & Newborn Health Nursing
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3. There is trophoblastic proliferation, with mitotic activity. This causes
excessive secretion of HCG, chorionic thyrotrophin and progesterone.
On the other hand, oestrogen production is low due to absence of the
fetal supply of precursors.
4. High HCG causes multiple theca lutein cysts in the ovaries in about
50% of cases. It also results in exaggeration of the normal early
pregnancy symptoms and signs.
Types:
1. Complete mole:
• The whole conceptus is transformed into a mass of vesicles.
• No embryo is present.
• It is the result of fertilization of a nucleated ovum (has no
chromosomes) with a sperm, which will duplicate giving rise to 46
chromosomes of paternal origin only.
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