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site of infection in endogenous endophthalmitis. For this reason, biopsies should be
taken from the area that is the primary site of ocular inoculation/inflammation.
List of commonly used antibiotics with recommended doses:
Antibiotic Topical Subconjunctival Intravitreal
Amikacin 20mg/ml 40mg/ml 400micgm
Amphotericin B 0.15-0.5% - 5-10micgm
Ampicillin 50mg/ml 100mg 5mg
Cefazoline 50mg/ml 100mg 2.25mg
Ceftazidime 50mg/ml 100mg 2.25mg
Ciprofloxacin 0.3% 1mg 100-500micgm
Clindamycin - 30mg 250micgm
Fluconazole 0.2% 2%-1ml 10-100micgm
Gatifloxacin 0.3% - 400micgm
Gentamicin 10-20mg/ml 20mg 200micgm
Levofloxacin 0.5% - 625micgm
Miconazole 10mg/ml 5mg 25micgm
Moxifloxacin 0.5% - 400micgm
Tobramycin 8-15mg/ml 20mg 200micgm
Vancomycin 50mg/ml 25mg 1mg
Voriconazole 1-2% - 100micgm
Standard Operating procedure
a. In Patient
All patients with endophthalmitis should be admitted and treated as in patients
b. Out Patient
Not applicable
c. Day Care
Not applicable
d)Referral criteria:
i) Postoperative endophthalmitis with presenting vision of light perceptions.
ii) Severe postoperative endophthalmitis
iii) Traumatic endophthalmitis with lens rupture and intraocular foreign body.
iv) Endogenous endophthalmitis worsening in spite of maximum treatment
v) Endophthalmitis in the only seeing eye
vi) Paediatric patients needing general anaesthesia
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