Page 17 - NAME OF CONDITION: REFRACTIVE ERRORS
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papillary size. If this be the case, it is interesting to speculate whether the treated area
                    corrects  the  aberrations,  over  the  entire  spectrum  of  papillary  dilatation  and

                    constriction, which happens during our day to day activities.
                5.  Limitation of the retina: Even if we correct all the aberrations of the eye, there is a
                    biological limitation of the retina to see beyond approximately 6/3 vision. It is not clear
                    whether the neural retina will be able to interpret the improved image.
                6.  Depth of field: Removing the eye’s higher order aberrations increases optical quality
                    for objects that lie at the best focus. However, it reduces optical quality for objects that
                    are  far  out  of  best  focus.  Exactly  how  this  benefits  and  cost  tradeoff  functions  in
                    everyday vision has not yet been carefully studied.
                7.  Change  in  posture:  It  has  to  be  understood  that  the  wave  front  measurements  are
                    taken  with  the  patient  in  a  sitting  position,  while  the  treatment  is  performed  in  a

                    patient  in  a  supine  position.  Since  the  wave  front  changes  with  these  postural
                    alterations, this factor needs to be studied in detail.

                Contraindications
                •  Unstable refraction
                •  Certain abnormalities of the cornea (e.g., keratoconus or other corneal ectasias,
                    thinning, edema, interstitial or neurotrophic keratitis, extensive vascularization)
                •  Insufficient corneal thickness for the proposed ablation depth

                •  Visually significant cataract
                •  Uncontrolled glaucoma

                •  Uncontrolled external disease (e.g., blepharitis, dry eye syndrome, atopy/allergy)
                •  Uncontrolled connective tissue or autoimmune disease
                •  Unrealistic patient expectations
                Relative Contraindications
                •  Functional monocularity

                •  Ocular conditions that limit visual function
                •  Excessively steep or flat corneas
                •  Abnormal corneal topography suggestive of forme fruste of keratoconus, keratoconus,
                    or other corneal ectasias

                •  Significant irregular astigmatism
                •  Corneal stromal or endothelial dystrophies
                •  History of herpes simplex virus (HSV) or varicella zoster virus (VZV) keratitis
                •  Significant dry eye syndrome
                •  Prior incisional or lamellar keratorefractive surgery

                •  Glaucoma
                •  Diabetes mellitus

                •  Pregnancy or lactation

                •  Connective tissue or autoimmune diseases

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