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486 Atlas of Small Animal CT and MRI
Figure 4.6.36 Pulmonary Fibrosis and Mineralization (Canine) CT
(a) DX, RLAT (b) DX, DV
(c) CT, TP (d) CT, TP (e) CT, TP
12y FS Miniature Pinscher with chronic renal failure, probable hyperadrenocorticism, and recent onset of respiratory compromise. There
is a generalized mild to moderate unstructured interstitial pattern on thoracic radiographs (a,b). There is diffuse and uniform increased
pulmonary attenuation on CT images (c–e), with an average of approximately −635 HU. There are focal regions of more pronounced
hyperattenuation in subpleural parenchyma of the caudal lung lobes (e: arrowheads). Pathologic diagnosis following postmortem exami-
nation was marked diffuse interstitial fibrosis and mineralization. Mineralization of the basement membrane in the lung was thought to
contribute to acute tachypnea and dyspnea.
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