Page 27 - PC 101 practical notes 24-25..

MANSOURA NATIONAL UNIVERSIY
PHARM D- CLINICAL PHARMACY LEVEL I PHARM. ANAL. CHEM. I (PC 101)

A An no ot th he er r e ex xa am mp pl le e

Titration of 10 ml NaOH sample against 0.1 N H 2SO 4, if the end point is 4 mL,

calculate the concentration of NaOH sample (M.W. of NaOH = 40).

Solution:

H 2SO 4 + 2 NaOH → Na 2SO 4 + 2 H 2O

 1 H 2SO 4 ≡ 2 NaOH

standard sample

Equivalence factor (F):

2 x M.W. of NaOH x 0.1
each ml of 0.1 N H 2SO 4 ≡ ≡ 0.004 g NaOH
2 x 1000

Concentration:

4 x 0.004 x 1000
Concn. of NaOH = = 1.6 g/L
10

= 0.16 g%

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