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        10.    Rudy Y, Silva JR. Computational biology in the study of cardiac ion channels and cell

        electrophysiology. Q Rev Biophys. 2006 Feb;39(1):57-116. doi: 10.1017/S0033583506004227. Epub
        2006 Jul 19. PMID: 16848931; PMCID: PMC1994938.


        11.    Hodgkin AL, Huxley AF. A quantitative description of membrane current and its application

        to conduction and excitation in nerve. J Physiol. 1952 Aug;117(4):500-44. doi: 10.1113/jphysiol.1952.
        sp004764. PMID: 12991237; PMCID: PMC1392413.


        12.    Armstrong CM, Bezanilla F. Inactivation of the sodium channel. II. Gating current

        experiments. J Gen Physiol. 1977 Nov;70(5):567-90. doi: 10.1085/jgp.70.5.567. PMID: 591912; PMCID:
        PMC2228472.


        13.    Bezanilla F, Armstrong CM. Inactivation of the sodium channel. I. Sodium current

        experiments. J Gen Physiol. 1977 Nov;70(5):549-66. doi: 10.1085/jgp.70.5.549. PMID: 591911; PMCID:
        PMC2228478.


        14.    Luo CH, Rudy Y. A dynamic model of the cardiac ventricular action potential. I.

        Simulations of ionic currents and concentration changes. Circ Res. 1994 Jun;74(6):1071-96.
        doi: 10.1161/01.res.74.6.1071. PMID: 7514509.


        14a.   Luo CH, Rudy Y. A dynamic model of the cardiac ventricular action potential. II. Afterde-

        polarizations, triggered activity, and potentiation. Circ Res. 1994 Jun;74(6):1097-113. doi: 10.1161/01.
        res.74.6.1097. PMID: 7514510.


        15.    Faber GM, Rudy Y. Action potential and contractility changes in [Na(+)](i) overloaded

        cardiac myocytes: a simulation study. Biophys J. 2000 May;78(5):2392-404. doi: 10.1016/S0006-
        3495(00)76783-X. PMID: 10777735; PMCID: PMC1300828.


        16.    Hund TJ, Rudy Y. Rate dependence and regulation of action potential and calcium transient

        in a canine cardiac ventricular cell model. Circulation. 2004 Nov 16;110(20):3168-74. doi: 10.1161/01.
        CIR.0000147231.69595.D3. Epub 2004 Oct 25. PMID: 15505083; PMCID: PMC1851913.


        17.    Decker KF, Heijman J, Silva JR, Hund TJ, Rudy Y. Properties and ionic mechanisms of action

        potential adaptation, restitution, and accommodation in canine epicardium. Am J Physiol Heart
        Circ Physiol. 2009 Apr;296(4):H1017-26. doi: 10.1152/ajpheart.01216.2008. Epub 2009 Jan 23.
        PMID: 19168720; PMCID: PMC2670702.



        18.    O'Hara T, Virág L, Varró A, Rudy Y. Simulation of the undiseased human cardiac
        ventricular action potential: model formulation and experimental validation. PLoS Comput Biol.
        2011 May;7(5):e1002061. doi: 10.1371/journal.pcbi.1002061. Epub 2011 May 26. PMID: 21637795;
        PMCID: PMC3102752.
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