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A28    SCIENCE
               Saturday 20 January 2018

            Gov't scientists scramble to save research ahead of shutdown



            By LAURAN NEERGAARD                                                                    "You  have  experiments      attempts,  the  hurdles  to
             AP Medical Writer                                                                     that  have  been  going  on   getting  an  HIV  vaccine
            WASHINGTON  (AP)  —  The                                                               for months if not years, and   are "surmountable," but ex-
            nation's  premier  medical                                                             then all of a sudden you've   pect such a shot to be only
            research  institute  is  in  "a                                                        got to stop — you can't do   partially  effective.  Even
            scramble"  to  prepare  for                                                            that," Fauci said. "You can't   a  vaccine  that's  50  to  60
            a partial government shut-                                                             push the pause button on     percent  effective  "would
            down that could ruin costly                                                            an  experiment  when  you    be  a  home  run"  because
            experiments and leave sick                                                             inject  an  animal  with  a   it  could  be  combined
            patients  unable  to  enter                                                            particular substance to see   with  condoms,  preventive
            cutting-edge  studies,  Dr.                                                            what  the  response  is  and   medications  and  other
            Anthony  Fauci  of  the  Na-                                                           then you have to go home     steps, Fauci said.
            tional  Institutes  of  Health                                                         for a week."                 "When  you  put  even  a
            said Thursday.                                                                         In a wide-ranging interview   modestly   effective   HIV
            Fauci stressed that patients                                                           Thursday, Fauci also said:   vaccine  together  with  all
            currently  in  NIH-run  stud-                                                          —  It's  too  soon  to  know   of  the  other  prevention
            ies  —  including  those  at                                                           how well this year's flu vac-  modalities, I think we could
            the  research-only  hospital                                                           cine  is  protecting  against   put an end to the epidem-
            often  called  the  "house                                                             the  tough  virus  strain  hit-  ic.  That's  what  I  hope  we
            of  hope"  —  wouldn't  be                                                             ting  much  of  the  country.   can  do  at  least  while  I'm
            adversely  affected  even    Dr. Anthony Fauci of the National Institutes of Health speaks dur-  Probably the flu shot will be   still alive," he said.
            if  President  Donald  Trump   ing an AP Newsmaker interview in Washington, Thursday, Jan.   about  30  percent  effec-  —Science has the capabil-
            and Congress don't reach     18, 2018.                                                 tive, he estimated, and he   ity, given the right resourc-
            a  budget  deal  to  avert  a                                         Associated Press  said  science  must  come   es,  to  create  vaccines  for
            shutdown  at  midnight  Fri-  described how researchers   tial  shutdown  —  and  who   up  with  better  protection   tuberculosis  and  malaria,
            day.  "We  still  take  care  of   working  on  projects  from   would  be  barred.  There's   against the constantly mu-  as well as HIV. Tackling all
            them,"  Fauci,  the  NIH's  in-  cancer  therapies  to  new   also  a  potential  ripple  ef-  tating virus.        three, "you're talking about
            fectious disease chief, told   vaccines  are  figuring  out   fect,  because  NIH  funds   He  is  prioritizing  develop-  millions and millions of lives
            The Associated Press. "You   how to try to save work in   basic  research  and  clini-  ment of a universal flu vac-  per year that you'll be sav-
            never want to put patients   progress  so  it  wouldn't  go   cal trials at universities and   cine  to  protect  against   ing." —Zika may have fad-
            in any jeopardy."            to waste.                    other institutions across the   both  seasonal  flu  and  su-  ed from the headlines but
            But new patients attempt-    "It's  a  scramble,"  Fauci   country.                    per-strains that can trigger   if it rebounds in Latin Amer-
            ing  to  enter  studies  of  ex-  said,  offering  a  peek  at   Fauci, who directs the Na-  pandemics.  How  soon?   ica,  NIH  has  "a  vaccine
            perimental  therapies,  of-  the practical impact of the   tional  Institute  of  Allergy   "Years,  not  decades,"  he   ready  to  go  and  prove
            ten because they've failed   budget impasse.              and  Infectious  Diseases,   said.  Meanwhile,  get  the   whether  it's  effective  or
            standard treatment, would    As  at  other  federal  agen-  called  the  cycle  of  off-  regular  flu  vaccine:  "Any   not."  Perhaps  more  impor-
            have  to  be  turned  away,   cies,  NIH  must  determine   and-on budget deals and    degree  of  protection  is   tant, it was made in a way
            as  happened  during  the    who  is  an  "essential"  em-  shutdown threats demoral-  better  than  no  protection   that  NIH  thinks  could  be
            last government shutdown.    ployee  and  would  report   izing  and  disruptive  to  sci-  at all."                copied quickly to fend off
            And  across  the  NIH,  Fauci   to  work  if  there  is  a  par-  ence.                —Despite  years  of  failed   other emerging viruses.q

                                                                      Expert says major eruption in


                                                                      Papua New Guinea could be soon



                                                                      CANBERRA,  Australia  (AP)   recently   increased   be-   two  boats  to  completely
                                                                      — Seismic activity beneath   neath the volcano.           evacuate the 600 Kadovar
                                                                      a Papua New Guinea vol-      "The  reason  we're  getting   residents to the mainland.
                                                                      cano  could  mean  that  a   activity  is  probably  be-  He  could  not  say  whether
                                                                      major  eruption  was  immi-  cause new magma is mov-      the evacuations of nearby
                                                                      nent, a scientist said Thurs-  ing up from deeper down,"   islands had been complet-
                                                                      day.                         Saunders  told  Australian   ed by Thursday.
                                                                      Thousands of people have     Broadcasting Corp.           Papua New Guinea sits on
                                                                      been  evacuated  from  is-   Prime Minister Peter O'Neill   the "Ring of Fire," a line of
                                                                      lands surrounding Kadovar    has  said  state  resources   seismic faults encircling the
            In this photo taken on Tuesday, Jan. 16, 2018, ash plumes rise   Island off the South Pacific   were  being  made  avail-  Pacific  that  has  frequent
            from the volcano on Kadovar Island, Papua New Guinea in the   nation's  north  coast  since   able  to  support  evacua-  earthquakes and volcanic
            South Pacific.                                            a  volcano  there  began     tions and he warned north-   eruptions.q
                                                     Associated Press  erupting  on  Jan.  5,  spout-  ern coastal communities to
                                                                      ing  ash.  Flights  nearby   be alert for possible tsuna-
                                                                      have been canceled due       mis. Kadovar is offshore to
                                                                      to  the  risk  posed  by  ash   the  north  of  New  Guinea,
                                                                      plumes  and  ships  were     the  larger  island  that  in-
                                                                      warned to stay away from     cludes  Papua  New  Guin-
                                                                      the island.                  ea's capital, Port Moresby.
                                                                      Steve  Saunders,  principal   Aikari Muri, the Internation-
                                                                      geodetic  surveyor  at  the   al  Red  Cross'  disaster  risk
                                                                      Rabaul  Volcano  Observa-    management logistics offi-
                                                                      tory in Papua New Guinea,    cer for Papua New Guinea,
                                                                      said  seismic  activity  had   said  the  military  had  used
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