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What is Venous   Virchow’s



 Thromboembolism (VTE)?  Triad                                                   BLOOD FLOW

                                                                                   STASIS

                  Rudolf Virchow (1821-1902) is known
                  as the father of modern pathology.
 Venous thromboembolism (VTE) is a condition in which a blood clot forms most often in the   Virchow’s research and discoveries
 deep veins of the leg, groin or arm (known as deep vein thrombosis, DVT) and travels in the   are instrumental to the modern
 circulation, lodging in the lungs (known as pulmonary embolism, PE). Together, DVT and PE   understanding of pathological   ENDOTHELIAL  HYPERCOAGULABILITY
 are known as VTE - a dangerous, potentially deadly medical condition. 13  INJURY
                  treatments and human anatomy. His
                  triad of thrombosis and embolism
                  describes the three events necessary
                  for clotting to occur. As medicine has
                  evolved, the understanding of blood clots has as well, and a clear link between
 Embolus          bed rest and clotting was uncovered. Since a provoking 1944 JAMA article, the
 Travels to Lungs  evils of bed rest have been well documented, and early indications of VTE as an
                  “ambulatory disease” has further linked bed rest and thrombosis. More recently
                  the challenges of the 2020 global pandemic have once again brought coagulation
                  issues to the forefront of the medical community.



                                                            THE EVIL SEQUELAE OF COMPLETE
                                                                       BED REST                   1944, Journal of
                                                                     WILLIAM DOC, M.D.            American Medical
 Normal Blood Flow Deep Vein                                            LOS ANGELES               Association
 Thrombosis                                                It is rarely possible to ascribe to bed rest alone the
                                                             disorders which become manifest in patients



                  Mechanical Prophylaxis & Anticoagulants

 A Deadly Silent Killer

                  In the hospital, blood clot prevention is attacked from two angles, thinning the blood
                  through pharmacological agents and replicating ambulation to mechanically move blood
 Deep Vein Thrombosis (DVT), a thrombosis in the deep vein of the leg, is a leading cause of   through the circulatory system. Pharmacological therapy can have limitations with specific
 preventable hospital mortality, affecting 350,000-900,000 patients with an estimated   patient populations due to bleeding risk and drug-to-drug interactions.
 60,000-100,000 annual deaths in the United States.
 5
                  Association of periOperating Room Nurses (AORN) and American College of Chest
                  Physicians (ACCP) Guidelines recommend mechanical prophylaxis for at least 18 hours
 DVTs are the fifth most common reason for hospital readmission, the third most frequent   per day for various patient types and prior to anesthesia for a surgical operation and
 complication of total joint replacement (TJR), and are associated   immediately afterward.
 with an estimated annual cost of $10 billion. 5




 44  MO V EMEN T AND  C O MP RES S IO NS  SY ST EM                            MO V EMEN T AND  C O MP RES S IO NS  SY ST EM  55
                                                                              MOVEMENT AND COMPRESSIONS SYSTEM
 MOVEMENT AND COMPRESSIONS SYSTEM
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