Page 34 - BSAVA Guide to Pain Management in Small Animal Practice
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4  |  Chronic and osteoarthritic pain



        VetBooks.ir  examination, further diagnostic imaging and   Treatment of chronic pain
               Based on the history and clinical
                                                   Chronic pain has many di erent aetiologies and
             haematological biochemical evaluation may be
             necessary. If the aetiology is identi able, a   these should be considered when devising a
             resolution may be possible, but in many cases   treatment plan.  he goal of treatment is the
             long-term palliative treatments will be required.   provision of e ective analgesia with minimal
              he use of a  uestionnaire at each visit will help   side e ects.  any di erent analgesics can be
             to tailor the treatment plan and assess   used and the agents are listed in  igures 4.
             improvement or deterioration.          dogs  and 4.4  cats , with suggested algorithms
                                                   for approaches to treatment outlined in  igures
                                                   4.   dogs  and 4.6  cats .


                            Dose                           Comments
             Carprofen          mg kg orally    h  or divided in two   Indicated for musculoskeletal disorders
                            doses  for   days, then reduced to   mg kg   and DJD
                            daily depending on clinical response
             Cimicoxib        mg kg orally    h            Indicated for pain and in ammation of  A
              eracoxib          mg kg orally    h          Indicated for OA in USA
                                                           No MA in UK
             Etodolac             mg kg orally    h        Indicated for OA in USA
                                                           No MA in UK
              irocoxib        mg kg orally    h            Indicated for OA in dogs
                                                            ield trials limited to 9  days
             Grapiprant       mg kg orally    h            Indicated for OA
             Paracetamol          mg kg orally      h
              acetaminophen      mg kg i.v.    h
             Phenylbutazone     mg kg orally    h  preferably divided in   Indicated for OA, rheumatoid and other
                            two or three doses  for   days, then    mg   arthritic diseases
                            kg    h  divided in two or three doses
             Prednoleucotropin      mg kg cinchophen and  .    mg kg   Indicated for OA, 14 day trial followed by
              PL            prednisolone orally q12h       14 days free of treatment
             (cincophen and
             prednisolone
              avacoxib        mg kg orally once then repeated    days   Indicated for pain and in ammation of
                            later, then monthly for up to 6 months
              eloxicam       .  mg kg orally    h on day  , followed by   Indicated for pain and in ammation in
                             .  mg kg orally               chronic musculoskeletal disorders
             Robenacoxib        mg kg orally    h          Indicated for pain and in ammation of
                                                           chronic OA
              epoxalin            mg kg orally    h on day   followed   Indicated for OA
                            by    mg kg orally    h
                    Non steroidal anti in ammatory drugs  NSAI s  and other anti in ammatory and pain relieving products
                3   for use in dogs with chronic maladaptive pain. Very few products have long term market authori ation
               A  and treatment must be closely supervised by a veterinary surgeon. Consult datasheets for further information.
             Use the lowest e ective dose and a multimodal approach. All NSAI s are capable of causing gastrointestinal signs
             and lesions, and hepatic and renal in ury. Regular monitoring of patients is necessary.       degenerative  oint
             disease;  A   osteoarthritis.

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