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Technical Aspects of Fluid Therapy  381



            3. One 30-inch intravenous extension tubing set if
              needed
            4. Three-way stopcock if needed
            5. 20-mL syringe filled with saline solution
            6. 20-gauge needle
              The manometer and tubing are primed with saline
            solution, and the column is filled to a level well above
            the anticipated CVP of the patient. The animal is posi-
            tioned in sternal or lateral recumbency with lateral recum-
            bency preferred for accuracy. The stopcock at the bottom
            of the manometer column should rest on the table or cage
            floor. When the stopcock is turned to connect the column
            of saline with the catheter, the hydrostatic pressure in the
            column forces fluid through the catheter. The saline col-  Figure 15-13 Measurement of central venous pressure (CVP)
            umn continues to fall until the hydrostatic pressure of the  using a saline column manometer. The dog is positioned in lateral
            column reaches equilibrium with the hydrostatic pressure  recumbency, and the manometer rests on the table surface. The
            of the blood at the end of the catheter. When it has  location of the patient's midline was estimated to be level with the
            reached equilibrium and has stopped decreasing, the  “0” mark on the column, and the marker ring has been slid to
            height of the saline column above the catheter tip,  that point (large arrow). The saline column has stopped falling, and
                                                                the ball floating on the top of the saline column rests at 4.5 cm at
            expressed as centimeters of water, reflects the blood pres-  the end of expiration (small arrow). Therefore this patient's CVP is
            sure within the vessel at the catheter tip. Therefore it is  read as 4.5 – 0 ¼ 4.5 cm of water.
            important to know approximately where the catheter
            tip lies in relation to the manometer fluid column. When
            the animal is in lateral recumbency, the cranial vena cava  the beginning of diastole (Figure 15-14). The response
            lies near the midline, and the sternum is a good reference  of the fluid column in the manometer is too slow to show
            point. In sternal recumbency, the cranial vena cava is  all of the peaks and valleys of these pressure changes accu-
            approximately level with the point of the shoulder  rately. When using a water column manometer, the best
            (scapulohumeral) joint.                             method is to measure the CVP just before inspiration
              When the appropriate external anatomic landmark is  and at the lowest diastolic swing. This value correlates
            found, the manometer column is positioned with the  best with real CVP. 11  If the rhythmic fluctuations are
            stopcock resting on the table surface immediately next  absent, malpositioning of the catheter should be
            to the landmark, and the centimeter mark nearest that  suspected: either it is too short or too long and the tip
            point is labeled. This mark is now the zero reference point  is not within the thoracic cavity, or the tip is butted up
            on the manometer, and all subsequent measurements are  against a vessel wall or the right atrial wall. Obstruction
            read as the distance from that mark. Measurements can be  of the catheter tip can be confirmed by aspirating blood
            made with the manometer located anywhere nearby that  from the catheter: blood flows rapidly and with little resis-
            is convenient, as long as the stopcock rests on the same  tance if it is floating freely within the lumen of the vessel.
            horizontal surface as the animal (Figure 15-13). If the  A high CVP or the presence of large fluctuations synchro-
            animal is in a cage, the manometer may be taped to  nous with the heartbeat suggests that the catheter tip is in
            the wall of the cage and used there.                the lumen of the right ventricle; if this is the case, it should
                                                                be partially withdrawn to the proper level. Dorsal recum-
            INTERPRETATION                                      bency, abdominal compartment syndrome, or pleural
            When   obtaining  a  CVP  measurement,  rhythmic    effusion will increase the CVP and may lead to erroneous
            fluctuations in the height of the saline column meniscus  assumptions about the cardiovascular system if the
            are usually seen. These oscillations are caused by two  pressure influence of those syndromes is not taken into
            factors: large ones occur with respiration, and smaller  consideration. 19,29
            ones occur with each heartbeat. Fluctuations in the col-  Water manometers tend to overestimate CVP by 0.5 to
            umn synchronized with respirations are usually easily  5cm H 2 O; this overestimation varies from patient to
            seen. As the patient inhales, the intrathoracic pressure  patient and from measurement to measurement in the
            and CVP decrease; the reverse occurs during exhalation.  same patient, even when positioning is done as carefully
            These excursions are exaggerated in animals with upper  as possible. 11  This variation can be important when
            airway obstruction and are reversed by positive pressure  following a critically ill animal that requires aggressive
            ventilation. With regard to the cardiac cycle, CVP  fluid support and in animals that are hyperventilating,
            increases steadily until atrial contraction, jumps up a bit  dyspneic, or being treated with positive pressure
            during atrial contraction, and then decreases rapidly at  ventilation. A calibrated electronic pressure transducer
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