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Chapter 1: Heart Murmurs and Gallop Heart Sounds  7



                Box 1.2.  Websites	with	libraries	of	digital	heart	and	respira-  Box 1.3.  Grading	of	murmurs	(6	grade	scale)
                tory	sounds
                                                                  Grade 1:	a	very	soft,	localized	murmur	detected	only	in	a
                Veterinary                                          quiet	room	after	intense	listening
                http://cal.vet.upenn.edu/projects/newsmcardiac/default.htm  Grade 2:	a	soft	murmur,	heard	immediately,	localized	to	a
                http://www.vetgo.com/cardio/index.php               single	area                                         Clinical Entities
                                                                  Grade 3:	a	moderate-intensity	murmur	that	is	evident	at
                Human
                                                                    more	than	one	location
                http://depts.washington.edu/physdx/heart/demo.html  Grade 4:	a	moderate-intensity	to	loud	murmur	that	radiates
                http://www.dundee.ac.uk/medther/Cardiology/hsmur.html
                                                                    well,	but	a	consistent	precordial	thrill	is	not	present
                http://www.med.umich.edu/lrc/coursepages/M1/anatomy/  Grade 5:	a	loud	murmur	accompanied	by	a	palpable
                  html/surface/thorax/hsounds.html
                                                                    precordial	thrill
                http://www.blaufuss.org/                          Grade 6:	a	loud	murmur	with	a	precordial	thrill,	audible
                http://www.bioscience.org/atlases/heart/sound/sound.htm
                                                                    when	the	stethoscope	is	removed	from	the	thorax
                http://www.med.ucla.edu/wilkes/intro.html
                http://www.medstudents.com.br/cardio/heartsounds/
                  heartsou.htm                                   vessel  with  rapid  flow,  or  when  blood  viscosity  is
                http://www.csulb.edu/org/college/bme/respiratory_sounds/  decreased (with anemia), there is a tendency toward tur-
                  medic.htm                                      bulence. Rapid changes in vessel diameter such as occurs
                http://www.cvmbs.colostate.edu/clinsci/callan/breath_  with stenotic lesions may also lead to turbulent flow.
                  sounds.htm
                http://www.rale.ca/                              Classification of Heart Murmurs
                                                                 Murmurs are classified in several ways:
                                                                   Timing in the cardiac cycle (systolic, diastolic, continu-
              murmur along the right or left parasternum (Rishniw
              and Thomas 2002; Allen 2010). There are several good   ous). While most common cardiovascular diseases in the
              websites, which include libraries of normal and abnor-  cat result in systolic murmurs, occasionally feline patients
              mal heart and respiratory sounds, that are excellent for   will present with diseases such as mitral stenosis (which
              educational purposes. See Box 1.2 for a list of these sites.  results in a diastolic murmur) or patent ductus arteriosus
                                                                 (which results in a continuous cardiac murmur).
                                                                   Intensity  is  the  loudness  of  the  murmur  most  often
              HEART MURMURS
                                                                 graded using a 6-tier scale. See Box 1.3 for definitions in
              Cardiac murmurs are most often caused by the vibra-  this  classification  scheme.  The  intensity  of  the  murmur
              tions associated with high-velocity, disturbed, and tur-  does  not  necessarily  correlate  with  the  severity  of  the
              bulent blood flow. Such disturbances may be caused by   underlying heart disease, as some well tolerated abnormali-
              valvular insufficiency (regurgitation), valvular stenosis,   ties (such as restrictive/resistive ventricular septal defects)
              or the presence of a shunt. Disturbed flow that is low   produce very loud murmurs, while some severe lesions may
              velocity,  such  as  pulmonic  valve  regurgitation/  produce soft murmurs (i.e., large unrestrictive/unresistive
              insufficiency,  may  not  be  auscultable.  Low-velocity   ventricular septal defect or severe tricuspid regurgitation).
              abnormal  flow  often  is  of  no  consequence  (e.g.,  pul-  Point  of  maximal  intensity  is  the  area  at  which  the
              monic valve regurgitation) but in some instances may   murmur is loudest, and it generally relates closely to the
              exist with a severe cardiac lesion (e.g., low-velocity flow   underlying source of turbulent flow. For example, a left-
              through a large atrial septal defect). Murmurs can also   to-right  patent  ductus  arteriosus  murmur  is  usually
              be created by other physiologic or pathological processes.   heard loudest over the left heart base at the pulmonary
              For example, murmurs are often heard with changes in   artery,  because  high-velocity  flow  from  the  aorta  is
              the viscosity of blood (anemia), and high-output dis-  shunting through the duct into the pulmonary artery at
              eases such as hyperthyroidism can be associated with the   this location.
              development of murmurs due to increased velocity of   Radiation  of  a  murmur  refers  to  how  widely  the
              ejected blood. The Reynolds number is used for predict-  murmur can be heard from the point of maximal inten-
              ing  whether  a  flow  pattern  is  likely  to  be  laminar  or   sity. Generally, the wider the radiation of the murmur,
              turbulent. Typically it is defined as v s L/v, where v s  is the   the greater the amount of turbulence being generated.
                                    −1
              mean fluid velocity in ms , L is the characteristic length   Pitch  and  quality  are  subjective  descriptions  of  the
              of the blood vessel in meters, and v is the kinematic fluid   character of a murmur (i.e., coarse, musical, etc.). These
                          2
              viscosity in m /s. Simplified, the relationship is inertial   descriptors  are  not  precise  and  do  not  have  the  same
              forces/viscous  forces.  Therefore,  in  a  large-diameter   objectivity as timing and point of maximal intensity.
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