Page 417 - Feline Cardiology
P. 417

Generic Name    Indications/Drug   Dosage and   Comments                           Available sizes
               (Brand Name)    Type            Possible Routes
                                               of Admin.

               Acepromazine    Phenothiazine   0.005–        •  Causes variable degrees of arteriodilation   10 mg/ml Inj VM
               (PromAce [V],   tranquilizer    0.02 mg/kg IV,   and reflex tachycardia, which can be
               AtraVet [V])                    or 0.01–      detrimental (myocardial oxygen deficit,
                                               0.1 mg/kg IM,   worsening of outflow tract obstruction, etc.).
                                               SQ            •  One of the most controversial drugs in
                                                             feline cardiovascular anesthesia, with some
                                                             cardiologists routinely advocating and using
                                                             low-dose protocols, and others considering
                                                             this drug contraindicated in all cats with
                                                             cardiovascular disease.
                                                             •  Higher doses generally reserved for cats
                                                             without cardiovascular disease.
                                                             •  Precautions if using this drug include: low
                                                             dosage (combined with other drugs such as
                                                             an opioid for adequate sedation), assessment
                                                             of perfusion during sedation, and avoidance
                                                             in elderly, dehydrated, or overtly ill patients.
                                                             •  Historically advocated for arteriodilation in
                                                             aortic thromboembolism, but no longer
                                                             because of lack of convincing benefit and risk
                                                             of adverse effects.
               Activase—see
               Tissue
               plasminogen
               activator
               Adrenaline—see
               Epinephrine

               Aldactone—see
               Spironolactone

               Altace—see
               Ramipril
               Alteplase—see
               Tissue
               plasminogen
               activator
               Amlodipine      Dihydropyridine-   0.625–     Drug of choice for treatment of hypertensive   2.5, 5, 10 mg
               (Norvasc [H])   type            1.25 mg/cat PO   cats when treatment of the underlying cause   Tab
                               (predominantly   q 24 h, may   is insufficient. Hypotension rare at standard   HM
                               arterial smooth   increase to q   dosages. Transdermal formulation not
                               muscle-specific)   12 h for   recommended due to unpredictable serum
                               calcium channel   refractory   amlodipine levels in hypertensive cats
                               blocker for     cases         (16–58% of equivalent serum levels compared
                               systemic                      to PO dosing in same cats).
      Drug Formulary  Antisedan—see
                               hypertension

               Atipamezole








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